SOC 29-1141 · Healthcare Practitioners and Technical Occupations · May 2025

How much do Registered Nurses make in Sioux Falls, SD-MN?

In the May 2025 Occupational Employment and Wage Statistics estimates, released May 15, 2026, the median annual wage for Registered Nurses in Sioux Falls, SD-MN is $75,350. The 10th percentile is $54,040 and the 90th percentile is $97,330. Employment is 7,680.

Median annual wage

$75,350

10th percentile
$54,040
25th percentile
$65,070
Median
$75,350
75th percentile
$81,690
90th percentile
$97,330
Mean
$74,700

Annual wage from the May 2025 OEWS estimates.

A welder at work with a torch
A welder at a bench, 2014. Photograph by Chetan Menaria. Wikimedia Commons · CC0

Percentile spread

For Registered Nurses, the published 10th percentile is $54,040 and the 90th percentile is $97,330. The difference is $43,290, which is 57.5% of the median. Ten percent of measured wages fall below the 10th percentile and ten percent fall above the 90th. How to read a percentile.

The middle half of the distribution, from the 25th percentile at $65,070 to the 75th at $81,690, covers $16,620.

The mean annual wage is $74,700, which sits below the median of $75,350. Median and mean measure different points in the same distribution.

National and state comparison

The Sioux Falls, SD-MN median is 22.8% lower than the national median of $97,550 for Registered Nurses. In 2024 national prices the local median is $83,139, which is 14.8% lower than that same national median. The national figure is already in national prices because the United States parity is 100.

It is 3.5% lower than the South Dakota median of $78,060.

Sioux Falls, SD-MN covers more than one state. The state comparison uses South Dakota, the primary state on the BLS area record.

Price-adjusted pay

The 2024 all-items regional price parity for Sioux Falls, SD-MN is 90.631, with the United States at 100. The Bureau of Economic Analysis released those parities on February 19, 2026. Dividing the May 2025 median of $75,350 by that parity and multiplying by 100 puts Registered Nurses at $83,139 in national prices. The wage year and the price year are different. Compare this wage after prices.

Nearby metros

7 other metropolitan areas within 200 miles publish a annual median for Registered Nurses. Sioux Falls, SD-MN ranks 8th of 8 on that median, counting itself. Distance is the great-circle mileage between Census Bureau internal points (U.S. Census Bureau, 2024 Gazetteer Files, Core Based Statistical Areas, internal points (INTPTLAT, INTPTLONG).).

  • Sioux City, IA-NE-SD is 76 miles away, with a median of $75,840 and employment of 1,600. That median is 0.7% higher than the median here. In 2024 national prices it is $87,723, against $83,139 here.
  • Mankato, MN is 143 miles away, with a median of $103,400 and employment of 1,570. That median is 37.2% higher than the median here. In 2024 national prices it is $113,683, against $83,139 here.
  • Omaha, NE-IA is 161 miles away, with a median of $84,600 and employment of 13,200. That median is 12.3% higher than the median here. In 2024 national prices it is $92,046, against $83,139 here.

Employment share

Registered Nurses accounts for 4.3% of wage-and-salary employment in Sioux Falls, SD-MN (7,680 of 178,590). Nationally the occupation is 2.2% of employment (3,379,720 of 155,495,730). The local share is 1.98 times the national share. That ratio is the location quotient computed from these May 2025 employment counts. It is not copied from the location-quotient column in the BLS bulk file.

Highest-paying jobs in Sioux Falls, SD-MN · Registered Nurses by metro · How to read these percentiles · Median and mean · When a wage is not published · How the figures are made · Compare this wage after prices

Questions this page answers

How much do Registered Nurses make in Sioux Falls, SD-MN?

In the May 2025 OEWS estimates, released May 15, 2026, the median annual wage for Registered Nurses in Sioux Falls, SD-MN is $75,350. The 10th percentile is $54,040 and the 90th percentile is $97,330. Employment is 7,680.

How does that compare with the national median for Registered Nurses?

The local median is 22.8% lower than the national median of $97,550.

What is Registered Nurses pay in Sioux Falls, SD-MN after local prices?

The 2024 all-items regional price parity for Sioux Falls, SD-MN is 90.631, with the United States at 100. In those national prices, the May 2025 median of $75,350 is $83,139. The wage is May 2025 and the parity is 2024.

How does Sioux Falls, SD-MN compare with nearby metros for Registered Nurses?

Sioux City, IA-NE-SD is the closest metropolitan area within 200 miles with a published annual median, 76 miles away, at $75,840. Sioux Falls, SD-MN ranks 8th of 8 metros within 200 miles on that median. Distances use Census Bureau internal points.