SOC 29-1071 · Healthcare Practitioners and Technical Occupations · May 2025

How much do Physician Assistants make in Sioux Falls, SD-MN?

In the May 2025 Occupational Employment and Wage Statistics estimates, released May 15, 2026, the median annual wage for Physician Assistants in Sioux Falls, SD-MN is $135,790. The 10th percentile is $106,660 and the 90th percentile is $158,520. Employment is 290.

Median annual wage

$135,790

10th percentile
$106,660
25th percentile
$110,150
Median
$135,790
75th percentile
$139,120
90th percentile
$158,520
Mean
$132,350

Annual wage from the May 2025 OEWS estimates.

An auto mechanic working on a car engine
An auto mechanic working on an engine. Photograph by Okpashira. Wikimedia Commons · CC BY-SA 4.0

Percentile spread

For Physician Assistants, the published 10th percentile is $106,660 and the 90th percentile is $158,520. The difference is $51,860, which is 38.2% of the median. Ten percent of measured wages fall below the 10th percentile and ten percent fall above the 90th. How to read a percentile.

The middle half of the distribution, from the 25th percentile at $110,150 to the 75th at $139,120, covers $28,970.

The mean annual wage is $132,350, which sits below the median of $135,790. Median and mean measure different points in the same distribution.

National and state comparison

The Sioux Falls, SD-MN median is 0.1% lower than the national median of $135,880 for Physician Assistants. In 2024 national prices the local median is $149,827, which is 10.3% higher than that same national median. The national figure is already in national prices because the United States parity is 100.

It is 1.9% higher than the South Dakota median of $133,200.

Sioux Falls, SD-MN covers more than one state. The state comparison uses South Dakota, the primary state on the BLS area record.

Price-adjusted pay

The 2024 all-items regional price parity for Sioux Falls, SD-MN is 90.631, with the United States at 100. The Bureau of Economic Analysis released those parities on February 19, 2026. Dividing the May 2025 median of $135,790 by that parity and multiplying by 100 puts Physician Assistants at $149,827 in national prices. The wage year and the price year are different. Compare this wage after prices.

Nearby metros

6 other metropolitan areas within 200 miles publish a annual median for Physician Assistants. Sioux Falls, SD-MN ranks 3rd of 7 on that median, counting itself. Distance is the great-circle mileage between Census Bureau internal points (U.S. Census Bureau, 2024 Gazetteer Files, Core Based Statistical Areas, internal points (INTPTLAT, INTPTLONG).).

  • Sioux City, IA-NE-SD is 76 miles away, with a median of $130,970 and employment of 70. That median is 3.5% lower than the median here. In 2024 national prices it is $151,491, against $149,827 here.
  • Mankato, MN is 143 miles away, with a median of $142,020 and employment of 70. That median is 4.6% higher than the median here. In 2024 national prices it is $156,143, against $149,827 here.
  • Omaha, NE-IA is 161 miles away, with a median of $134,130 and employment of 720. That median is 1.2% lower than the median here. In 2024 national prices it is $145,935, against $149,827 here.

Employment share

Physician Assistants accounts for 0.16% of wage-and-salary employment in Sioux Falls, SD-MN (290 of 178,590). Nationally the occupation is 0.10% of employment (162,150 of 155,495,730). The local share is 1.56 times the national share. That ratio is the location quotient computed from these May 2025 employment counts. It is not copied from the location-quotient column in the BLS bulk file.

Highest-paying jobs in Sioux Falls, SD-MN · Physician Assistants by metro · How to read these percentiles · Median and mean · When a wage is not published · How the figures are made · Compare this wage after prices

Questions this page answers

How much do Physician Assistants make in Sioux Falls, SD-MN?

In the May 2025 OEWS estimates, released May 15, 2026, the median annual wage for Physician Assistants in Sioux Falls, SD-MN is $135,790. The 10th percentile is $106,660 and the 90th percentile is $158,520. Employment is 290.

How does that compare with the national median for Physician Assistants?

The local median is 0.1% lower than the national median of $135,880.

What is Physician Assistants pay in Sioux Falls, SD-MN after local prices?

The 2024 all-items regional price parity for Sioux Falls, SD-MN is 90.631, with the United States at 100. In those national prices, the May 2025 median of $135,790 is $149,827. The wage is May 2025 and the parity is 2024.

How does Sioux Falls, SD-MN compare with nearby metros for Physician Assistants?

Sioux City, IA-NE-SD is the closest metropolitan area within 200 miles with a published annual median, 76 miles away, at $130,970. Sioux Falls, SD-MN ranks 3rd of 7 metros within 200 miles on that median. Distances use Census Bureau internal points.